Saffron vs. Memantine (Namenda) for Alzheimer’s
Volume 38
What’s the latest on treating memory disorders with the spice saffron? Saffron had evidently been “widely used in the Persian [medical tradition] for memory problems,” but it wasn’t put to the test—until this study, which I profiled, showing Alzheimer’s dementia symptoms continuing to get worse on placebo, but getting better on saffron over a 16-week period. The researchers concluded that, at least in the short term, saffron is “safe and effective in mild-to-moderate [Alzheimer’s disease].” What about head-to-head versus the leading drug used for such patients? It appeared to work just as well, but with significantly less vomiting—a common side effect of the drug. So, that’s where we were as of 2010. What’s the update?
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